EC 188.8.131.52 - Pancreatic elastase II
IntEnz Enzyme Nomenclature
- Preferential cleavage: Leu, Met and Phe. Hydrolyses elastin.
A peptidase of family S1 (trypsin family) formed by activation of proelastase II from mammalian pancreas by trypsin. Usually, only one of the pancreatic elastases (see also EC 184.108.40.206) is expressed in a given species; human pancreatic elastase is of type II.
Links to other databases
Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.Biochemistry 26 : 7256-7261 (1987). [PMID: 3427074]
Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2.J. Biochem. (Tokyo) 102 : 1555-1563 (1987). [PMID: 2834346]
[EC 220.127.116.11 created 1992]