EC - Pancreatic elastase II

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IntEnz Enzyme Nomenclature


Accepted name:
pancreatic elastase II
Other name:
pancreatic elastase 2
Systematic name:



A peptidase of family S1 (trypsin family) formed by activation of proelastase II from mammalian pancreas by trypsin. Usually, only one of the pancreatic elastases (see also EC is expressed in a given species; human pancreatic elastase is of type II.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00124
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004252
CAS Registry Number: 75603-19-9


  1. Fletcher, T.S., Shen, W.-F. and Largman, C.
    Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.
    Biochemistry 26 : 7256-7261 (1987). [PMID: 3427074]
  2. Shirasu, Y., Yoshida, H., Matsuki, S., Takemura, K., Ikeda, N., Shimada, Y., Ozawa, T., Mikayama, T., Iijima, H., Ishida, A., Sato, Y., Tamai, Y., Tanaka, J. and Ikenaga, H.
    Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2.
    J. Biochem. (Tokyo) 102 : 1555-1563 (1987). [PMID: 2834346]

[EC created 1992]