EC 3.4.21.2 - Chymotrypsin C

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IntEnz Enzyme Nomenclature
EC 3.4.21.2

Names

Accepted name:
chymotrypsin C
Other name:
caldecrin
Systematic name:
-

Reaction

Comments:

Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00124
Structural data: CSA , EC2PDB
CAS Registry Number: 9036-09-3
UniProtKB/Swiss-Prot:

References

  1. Peanasky, R.J., Gratecos, D., Baratti, J. and Rovery, M.
    Mode of activation and N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C.
    Biochim. Biophys. Acta 181: 82-92 (1969). [PMID: 5792601]
  2. Folk, J.E.
    Chymotrypsin C (porcine pancreas).
    Methods Enzymol. 19: 109-112 (1970).
  3. Wilcox, P.E.
    Chymotrypsinogens - chymotrypsins.
    Methods Enzymol. 19: 64-108 (1970).

[EC 3.4.21.2 created 1972]