EC 126.96.36.199 - γ-D-glutamyl-L-lysine dipeptidyl-peptidase
IntEnz view ENZYME view
IntEnz Enzyme Nomenclature
- The enzyme releases L-Ala-gamma-D-Glu dipeptides from cell wall peptides via cleavage of an L-Ala-gamma-D-GluL-Lys bond.
The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the recycling of the murein peptide.
Links to other databases
Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases.Biochemistry 40 : 15707-15715 (2001). [PMID: 11747447]
Structure of the gamma-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-gamma-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 : 1354-1364 (2010). [PMID: 20944232]
[EC 188.8.131.52 created 2015]