EC - γ-D-glutamyl-L-lysine dipeptidyl-peptidase

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IntEnz Enzyme Nomenclature


Accepted name:
γ-D-glutamyl-L-lysine dipeptidyl-peptidase
Other name:
Systematic name:



The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the recycling of the murein peptide.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Schmidt, D. M., Hubbard, B. K., Gerlt, J. A.
    Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases.
    Biochemistry 40 : 15707-15715 (2001). [PMID: 11747447]
  2. Xu, Q., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., Das, D., Deller, M. C., Duan, L., Ellrott, K., Farr, C. L., Feuerhelm, J., Grant, J. C., Grzechnik, A., Han, G. W., Jaroszewski, L., Jin, K. K., Klock, H. E., Knuth, M. W., Kozbial, P., Krishna, S. S., Kumar, A., Lam, W. W., Marciano, D., Miller, M. D., Morse, A. T., Nigoghossian, E., Nopakun, A., Okach, L., Puckett, C., Reyes, R., Tien, H. J., Trame, C. B., van den Bedem, H., Weekes, D., Wooten, T., Yeh, A., Hodgson, K. O., Wooley, J., Elsliger, M. A., Deacon, A. M., Godzik, A., Lesley, S. A., Wilson, I. A.
    Structure of the gamma-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-gamma-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 : 1354-1364 (2010). [PMID: 20944232]

[EC created 2015]