EC 3.2.2.16 - Methylthioadenosine nucleosidase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.2.2.16
Names
Accepted name:
methylthioadenosine nucleosidase
Other
names:
5'-methylthioadenosine nucleosidase
MTA nucleosidase
MeSAdo nucleosidase
methylthioadenosine methylthioribohydrolase
MTA nucleosidase
MeSAdo nucleosidase
methylthioadenosine methylthioribohydrolase
Systematic name:
S-methyl-5'-thioadenosine adeninehyrolase
Reaction
- S-methyl-5'-thioadenosine + H2O = 5-(methylsulfanyl)-D-ribose + adenine
Comments:
Unlike EC 3.2.2.9, this plant enzyme has little or no activity with S-adenosyl-L-homocysteine.
Links to other databases
Gene Ontology:
GO:0008930
CAS Registry Number:
50812-28-7
UniProtKB/Swiss-Prot:
MTN1_ARATH
References
-
5'-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds.Eur. J. Biochem. 114 : 293-299 (1981). [PMID: 6783408]
-
OsMTN encodes a 5'-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.).J. Exp. Bot. 58 : 1505-1514 (2007). [PMID: 17339651]
-
Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases.J. Mol. Biol. 378 : 112-128 (2008). [PMID: 18342331]
-
Biochemical and structural characterization of 5'-methylthioadenosine nucleosidases from Arabidopsis thaliana.Biochem. Biophys. Res. Commun. 381 : 619-624 (2009). [PMID: 19249293]
[EC 3.2.2.16 created 1983, modified 2003]