EC 3 - Hydrolases
EC 3.2 - Glycosylases
EC 3.2.1 - Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
EC 3.2.1.24 - α-mannosidase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.2.1.24
Names
Accepted name:
α-mannosidase
Other
names:
1,2-α-D-mannosidase
1,2-α-mannosidase
α-D-mannopyranosidase
α-D-mannosidase
p-nitrophenyl-α-mannosidase
exo-α-mannosidase
1,2-α-mannosidase
α-D-mannopyranosidase
α-D-mannosidase
p-nitrophenyl-α-mannosidase
exo-α-mannosidase
Systematic name:
α-D-mannoside mannohydrolase
Reaction
- Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides
Comments:
Also hydrolyses α-D-lyxosides and heptopyranosides with the same configuration at C-2, C-3 and C-4 as mannose.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Gene Ontology:
GO:0004559
CAS Registry Number:
9025-42-7
References
-
Presence of α-D-mannosidic linkage in glycoproteins. Liberation of D-mannose from various glycoproteins by α-mannosidase isolated from jack bean meal.J. Biol. Chem. 241 : 1010-1012 (1966). [PMID: 5905120]
-
Role of α-D-mannosidases in the biosynthesis and catabolism of glycoproteins.Biochem. Soc. Trans. 12 : 522-524 (1984). [PMID: 6428944]
[EC 3.2.1.24 created 1961]