EC 3.2.1.24 - α-mannosidase

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IntEnz Enzyme Nomenclature
EC 3.2.1.24

Names

Accepted name:
α-mannosidase
Other names:
1,2-α-D-mannosidase
1,2-α-mannosidase
α-D-mannopyranosidase
α-D-mannosidase
p-nitrophenyl-α-mannosidase
exo-α-mannosidase
Systematic name:
α-D-mannoside mannohydrolase

Reaction

Comments:

Also hydrolyses α-D-lyxosides and heptopyranosides with the same configuration at C-2, C-3 and C-4 as mannose.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004559
CAS Registry Number: 9025-42-7
UniProtKB/Swiss-Prot: (28) [show] [UniProt]

References

  1. Li, Y.-T.
    Presence of α-D-mannosidic linkage in glycoproteins. Liberation of D-mannose from various glycoproteins by α-mannosidase isolated from jack bean meal.
    J. Biol. Chem. 241: 1010-1012 (1966). [PMID: 5905120]
  2. Winchester, B.
    Role of α-D-mannosidases in the biosynthesis and catabolism of glycoproteins.
    Biochem. Soc. Trans. 12: 522-524 (1984). [PMID: 6428944]

[EC 3.2.1.24 created 1961]