EC 3.2.1.192 - Ginsenoside Rb1 β-glucosidase

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IntEnz Enzyme Nomenclature
EC 3.2.1.192

Names

Accepted name:
ginsenoside Rb1 β-glucosidase
Systematic name:
ginsenoside Rb1 glucohydrolase

Reaction

Comments:

Ginsenosidases catalyse the hydrolysis of glycosyl moieties attached to the C-3, C-6 or C-20 position of ginsenosides. They are specific with respect to the nature of the glycosidic linkage, the position and the order in which the linkages are cleaved. Ginsenoside Rb1 β-glucosidase specifically and sequentially hydrolyses the 20-[β-D-glucopyranosyl-(1→6)-β-D glucopyranosyloxy] residues attached to position 20 by first hydrolysing the (1→6)-glucosidic bond to generate ginsenoside Rd as an intermediate, followed by hydrolysis of the remaining 20-O-β-D-glucosidic bond.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Yan, Q., Zhou, W., Li, X., Feng, M., Zhou, P.
    Purification method improvement and characterization of a novel ginsenoside-hydrolyzing beta-glucosidase from Paecilomyces Bainier sp. 229.
    Biosci. Biotechnol. Biochem. 72: 352-359 (2008). [PMID: 18256474]

[EC 3.2.1.192 created 2014]