EC 3.2.1.18 - Exo-α-sialidase

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IntEnz Enzyme Nomenclature
EC 3.2.1.18

Names

Accepted name:
exo-α-sialidase
Other names:
α-neuraminidase
acetylneuraminidase
neuraminidase
sialidase
N-acylneuraminate glycohydrolase
Systematic name:
acetylneuraminyl hydrolase

Reaction

Comments:

The enzyme does not act on 4-O-acetylated sialic acids. An endo-α-sialidase activity is listed as EC 3.2.1.129 endo-α-sialidase. See also EC 4.2.2.15 anhydrosialidase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052794 , GO:0052795 , GO:0052796 , GO:0004308
CAS Registry Number: 9001-67-6
UniProtKB/Swiss-Prot: (222) [show] [UniProt]

References

  1. Schauer, R.
    Sialic acids.
    Adv. Carbohydr. Chem. Biochem. 40 : 131-234 (1982).
  2. Cabezas, J.A.
    Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase.
    Biochem. J. 278 : 311-312 (1991). [PMID: 1883340]

[EC 3.2.1.18 created 1961, modified 1999]