EC - α-agarase

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IntEnz Enzyme Nomenclature


Accepted name:
Other names:
agarase [ambiguous]
agarase A33
Systematic name:
agarose 3-glycanohydrolase




Requires Ca2+. The enzyme from Thalassomonas sp. can use agarose, agarohexaose and neoagarohexaose as substrate. The products of agarohexaose hydrolysis are dimers and tetramers, with agarotetraose being the predominant product, whereas hydrolysis of neoagarohexaose gives rise to two types of trimer. While the enzyme can also hydrolyse the highly sulfated agarose porphyran very efficiently, it cannot hydrolyse the related compounds κ-carrageenan (see EC and ι-carrageenan (see EC [2]. See also EC, β-agarase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033953


  1. Potin, P., Richard, C., Rochas, C. and Kloareg, B.
    Purification and characterization of the α-agarase from Alteromonas agarlyticus (Cataldi) comb. nov., strain GJ1B.
    Eur. J. Biochem. 214: 599-607 (1993). [PMID: 8513809]
  2. Ohta, Y., Hatada, Y., Miyazaki, M., Nogi, Y., Ito, S. and Horikoshi, K.
    Purification and characterization of a novel α-agarase from a Thalassomonas sp.
    Curr. Microbiol. 50: 212-216 (2005). [PMID: 15902469]

[EC created 2006]