EC - Fructan β-(2,1)-fructosidase

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IntEnz Enzyme Nomenclature


Accepted name:
fructan β-(2,1)-fructosidase
Other names:
β-(2-1)-D-fructan fructohydrolase
β-(2-1)fructan exohydrolase
1-fructan exohydrolase
1-FEH w1
1-FEH w2
β-(2-1)-linkage-specific fructan-β-fructosidase
β-(2,1)-D-fructan fructohydrolase
Systematic name:
β-(2→1)-D-fructan fructohydrolase



Possesses one of the activities of EC, fructan β-fructosidase. While the best substrates are the inulin-type fructans, such as 1-kestose (β-D-fructofuranosyl-(2→1)-β-D-fructofuranosyl α-D-glucopyranoside) and 1,1-nystose (β-D-fructofuranosyl-(2→1)-β-D-fructofuranosyl-(2→1)-β-D-fructofuranosyl α-D-glucopyranoside), some (but not all) levan-type fructans can also be hydrolysed, but more slowly [see EC, fructan β-(2,6)-fructosidase]. Sucrose, while being a very poor substrate, can substantially inhibit enzyme activity in some cases.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033948


  1. De Roover, J., Van Laere, A., De Winter, M., Timmermans, J.W. and Van den Ende, W.
    Purification and properties of a second fructan exohydrolase from the roots of Cichorium intybus.
    Physiol. Plant. 106 : 28-34 (1999). [PMID: 16526094]
  2. Van Den Ende, W., Clerens, S., Vergauwen, R., Van Riet, L., Van Laere, A., Yoshida, M. and Kawakami, A.
    Fructan 1-exohydrolases. β-(2,1)-Trimmers during graminan biosynthesis in stems of wheat? Purification, characterization, mass mapping, and cloning of two fructan 1-exohydrolase isoforms.
    Plant Physiol. 131 : 621-631 (2003). [PMID: 12586886]

[EC created 2005]