EC 3.2.1.15 - Endo-polygalacturonase

  IntEnz view ENZYME view
XML

IntEnz Enzyme Nomenclature
EC 3.2.1.15

Names

Accepted name:
endo-polygalacturonase
Other names:
endo-D-galacturonase
endogalacturonase
polygalacturonase [ambiguous]
pectin depolymerase [ambiguous]
pectin hydrolase
pectin polygalacturonase
pectinase [ambiguous]
pectolase
poly-α-1,4-galacturonide glycanohydrolase
poly(1,4-α-D-galacturonide) glycanohydrolase
Systematic name:
(1→4)-α-D-galacturonan glycanohydrolase (endo-cleaving)

Reaction

Comments:

The enzyme catalyses the random hydrolysis of (1→4)-α-D-galactosiduronic linkages in pectate and other galacturonans. Different forms of the enzyme have different tolerances to methyl esterification of the substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00415
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004650
CAS Registry Number: 9032-75-1
UniProtKB/Swiss-Prot: (89) [show] [UniProt]

References

  1. Deuel, H. and Stutz, E.
    Pectic substances and pectic enzymes.
    Adv. Enzymol. Relat. Areas Mol. Biol. 20 : 341-382 (1958). [PMID: 13605988]
  2. Lineweaver, H. and Jansen, E.F.
    Pectic enzymes.
    Adv. Enzymol. Relat. Subj. Biochem. 11 : 267-295 (1951).
  3. McCready, R.M. and Seegmiller, C.G.
    Action of pectic enzymes on oligogalacturonic acids and some of their derivatives.
    Arch. Biochem. Biophys. 50 : 440-450 (1954). [PMID: 13159344]
  4. Mill, P.J. and Tuttobello, R.
    The pectic enzymes of Aspergillus niger. 2. Endopolygalacturonase.
    Biochem. J. 79 : 57-64 (1961). [PMID: 13770689]
  5. Phaff, H.J. and Demain, A.L.
    The unienzymatic nature of yeast polygalacturonase.
    J. Biol. Chem. 218 : 875-884 (1956). [PMID: 13295238]

[EC 3.2.1.15 created 1961, modified 2019]