EC 3.2.1.143 - Poly(ADP-ribose) glycohydrolase

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IntEnz Enzyme Nomenclature
EC 3.2.1.143

Names

Accepted name:
poly(ADP-ribose) glycohydrolase
Systematic name:
-

Reaction

Comments:

Specific to (1''-2') linkage of ribose-ribose bond of poly(ADP-D-ribose).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004649
UniProtKB/Swiss-Prot: (15) [show] [UniProt]

References

  1. Miwa, M. and Sugimura, T.
    Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-ribose) by a calf thymus extract.
    J. Biol. Chem. 246: 6362-6364 (1971). [PMID: 4331388]
  2. Lin, W., Ame, J.C., Aboul-Ela, N., Jacobson, E.L. and Jacobson, M.K.
    Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase.
    J. Biol. Chem. 272: 11895-11901 (1997). [PMID: 9115250]

[EC 3.2.1.143 created 2000]