EC 126.96.36.199 - Diisopropyl-fluorophosphatase
IntEnz Enzyme Nomenclature
OPA anhydrase [ambiguous]
diisopropyl phosphorofluoridate hydrolase
organophosphate acid anhydrase
organophosphorus acid anhydrolase
- diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride
Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including 'nerve gases'). Inhibited by chelating agents; requires divalent cations. Related to EC 188.8.131.52 aryldialkylphosphatase. Previously listed as EC 184.108.40.206.
Links to other databases
Enzymatic hydrolysis of organophosphorus compounds. I. Occurrence of enzymes hydrolysing dimethyl-amido-ethoxy-phosphoryl cyanide (Tabun).Acta Chem. Scand. 8 : 753-761 (1954).
Enzymatic hydrolysis of organophosphorus compounds. II. Analysis of reaction products in experiments with Tabun and some properties of blood plasma tabunase.Acta Chem. Scand. 8 : 762-767 (1954).
Enzymatic hydrolysis of organophosphorus compounds. IV. Specificity studies.Acta Chem. Scand. 8 : 1533-1541 (1954).
Purification and properties of dialkylfluorophosphatase.Biochim. Biophys. Acta 26 : 29-39 (1957).
Enzymic hydrolysis of organophosphorus compounds.In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes , 2nd ed. vol. 4 , Academic Press , New York , 1960 , 541-550
In: Reiner, E., Aldridge, W.N. and Hoskin, C.G. (Eds.) Enzymes Hydrolysing Organophosphorus Compounds , Ellis Horwood Ltd. , Chichester, UK , 1989
[EC 220.127.116.11 created 1961 as EC 18.104.22.168, transferred 1992 to EC 22.214.171.124]