EC - Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

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IntEnz Enzyme Nomenclature


Accepted name:
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
Other names:
PpGpp phosphohydrolase
guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase
Systematic name:
guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008893
CAS Registry Number: 70457-12-4
UniProtKB/Swiss-Prot: (20) [show] [UniProt]


  1. Heinemeyer, E.-A. and Richter, D.
    Characterization of the guanosine 5'-triphosphate 3'-diphosphate and guanosine 5'-diphosphate 3'-diphosphate degradation reaction catalyzed by a specific pyrophosphorylase from Escherichia coli.
    Biochemistry 17 : 5368-5372 (1978). [PMID: 365225]
  2. Richter, D., Fehr, S. and Harder, R.
    The guanosine 3',5'-bis(diphosphate) (ppGpp) cycle. Comparison of synthesis and degradation of guanosine 3',5'-bis(diphosphate) in various bacterial systems.
    Eur. J. Biochem. 99 : 57-64 (1979). [PMID: 114395]

[EC created 1980]