EC 3.1.4.4 - Phospholipase D
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.1.4.4
Names
Accepted name:
phospholipase D
Other
names:
choline phosphatase
lecithinase D
lipophosphodiesterase II
lecithinase D
lipophosphodiesterase II
Systematic name:
phosphatidylcholine phosphatidohydrolase
Reactions
-
14445 [IUBMB]a 1,2-diacyl-sn-glycero-3-phosphocholineName origin: UniProt - CHECKED (C)Formula: C10H18NO8PR2
Charge: 0ChEBI compound status: CHECKED (C)H2OName origin: UniProt - CHECKED (C)Formula: H2O
Charge: 0ChEBI compound status: CHECKED (C)=a 1,2-diacyl-sn-glycero-3-phosphateName origin: UniProt - CHECKED (C)Formula: C5H5O8PR2
Charge: -2ChEBI compound status: CHECKED (C)cholineName origin: UniProt - CHECKED (C)Formula: C5H14NO
Charge: 1ChEBI compound status: CHECKED (C) -
a 1-acyl-sn-glycero-3-phosphocholineName origin: UniProt - CHECKED (C)Formula: C9H19NO7PR
Charge: 0ChEBI compound status: CHECKED (C)H2OName origin: UniProt - CHECKED (C)Formula: H2O
Charge: 0ChEBI compound status: CHECKED (C)=a 1-acyl-sn-glycero-3-phosphateName origin: UniProt - CHECKED (C)Formula: C4H6O7PR
Charge: -2ChEBI compound status: CHECKED (C)cholineName origin: UniProt - CHECKED (C)Formula: C5H14NO
Charge: 1ChEBI compound status: CHECKED (C) -
1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamineName origin: UniProt - CHECKED (C)Formula: C8H14NO7PR2
Charge: 0ChEBI compound status: CHECKED (C)H2OName origin: UniProt - CHECKED (C)Formula: H2O
Charge: 0ChEBI compound status: CHECKED (C)=1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphateName origin: UniProt - CHECKED (C)Formula: C6H7O7PR2
Charge: -2ChEBI compound status: CHECKED (C)ethanolamineName origin: UniProt - CHECKED (C)Formula: C2H8NO
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
Also acts on other phosphatidyl esters.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0070290
,
GO:0004630
CAS Registry Number:
9001-87-0
References
-
The bond hydrolyzed by cardiolipin-specific phospholipase D.Biochim. Biophys. Acta 296 : 79-88 (1973). [PMID: 4632675]
-
The enzymatically catalyzed release of choline from lecithin.J. Biol. Chem. 231 : 703-715 (1958).
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On the nature of the phosphorus-containing lipides of cabbage leaves and their relation to a phospholipide-splitting enzyme contained in these leaves.J. Biol. Chem. 172 : 191-198 (1948).
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Plant phospholipase D. I. Studies on cottonseed and cabbage phospholipase D.J. Biol. Chem. 218 : 213-224 (1956).
[EC 3.1.4.4 created 1961]