EC 3.1.3.97 - 3',5'-nucleoside bisphosphate phosphatase

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IntEnz Enzyme Nomenclature
EC 3.1.3.97

Names

Accepted name:
3',5'-nucleoside bisphosphate phosphatase
Systematic name:
nucleoside-3',5'-bisphosphate 3'-phosphohydrolase

Reaction

Comments:

The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. The enzyme has similar activity with ribonucleoside and 2'-deoxyribonucleoside 3',5'-bisphosphates, but shows no activity with nucleoside 2',5'-bisphosphates (cf. EC 3.1.3.7, 3'(2'),5'-bisphosphate nucleotidase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0097657
UniProtKB/Swiss-Prot:

References

  1. Cummings, J. A., Vetting, M., Ghodge, S. V., Xu, C., Hillerich, B., Seidel, R. D., Almo, S. C., Raushel, F. M.
    Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily.
    Biochemistry 53 : 591-600 (2014). [PMID: 24401123]

[EC 3.1.3.97 created 2015]