EC - L-galactose 1-phosphate phosphatase

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IntEnz Enzyme Nomenclature


Accepted name:
L-galactose 1-phosphate phosphatase
Other names:
VTC4 (gene name) [ambiguous]
IMPL2 (gene name) [ambiguous]
Systematic name:
β-L-galactose-1-phosphate phosphohydrolase



The enzyme from plants also has the activity of EC, inositol-phosphate phosphatase. The enzymes have very low activity with D-galactose 1-phosphate (cf. EC, D-galactose 1-phosphate phosphatase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Laing, W. A., Bulley, S., Wright, M., Cooney, J., Jensen, D., Barraclough, D., MacRae, E.
    A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis.
    Proc. Natl. Acad. Sci. U.S.A. 101: 16976-16981 (2004). [PMID: 15550539]
  2. Torabinejad, J., Donahue, J. L., Gunesekera, B. N., Allen-Daniels, M. J., Gillaspy, G. E.
    VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.
    Plant Physiol. 150: 951-961 (2009). [PMID: 19339506]
  3. Petersen, L. N., Marineo, S., Mandala, S., Davids, F., Sewell, B. T., Ingle, R. A.
    The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.
    Plant Physiol. 152: 1186-1196 (2010). [PMID: 20023146]

[EC, created 2014]