EC 3.1.3.88 - 5''-phosphoribostamycin phosphatase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 3.1.3.88

Names

Accepted name:
5''-phosphoribostamycin phosphatase
Other names:
btrP (gene name)
neoI (gene name)
Systematic name:
5''-phosphoribostamycin phosphohydrolase

Reaction

Comments:

Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. No metal is required for activity.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Kudo, F., Fujii, T., Kinoshita, S., Eguchi, T.
    Unique O-ribosylation in the biosynthesis of butirosin.
    Bioorg. Med. Chem. 15: 4360-4368 (2007). [PMID: 17482823]

[EC 3.1.3.88 created 2012]