IntEnz

EC 3.1.3.87 - 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase

IntEnz Enzyme Nomenclature
EC 3.1.3.87

Names

Reaction

• 14481 [IUBMB]
  2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate

  2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate

  Name origin: UniProt - CHECKED (C)

  CHEBI:59505

  Formula: C6H9O6PS
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

  +

  H₂O

  H2O

  Name origin: UniProt - CHECKED (C)

  CHEBI:15377

  Formula: H2O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  =

  1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one

  1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one

  Name origin: UniProt - CHECKED (C)

  CHEBI:49252

  Formula: C6H10O3S
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  phosphate

  phosphate

  Name origin: UniProt - CHECKED (C)

  CHEBI:43474

  Formula: HO4P
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

Comments:

The enzyme participates in the methionine salvage pathway in Bacillus subtilis [2]. In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and that of EC 5.3.2.5, 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [1].

Links to other databases

References

1. Myers, R. W., Wray, J. W., Fish, S., Abeles, R. H.
   Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
   J. Biol. Chem. 268 : 24785-24791 (1993). [PMID: 8227039]
2. Ashida, H., Saito, Y., Kojima, C., Kobayashi, K., Ogasawara, N., Yokota, A.
   A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
   Science 302 : 286-290 (2003). [PMID: 14551435]

[EC 3.1.3.87 created 2012]