EC 3.1.3.84 - ADP-ribose 1''-phosphate phosphatase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 3.1.3.84

Names

Accepted name:
ADP-ribose 1''-phosphate phosphatase
Other names:
POA1
Appr1p phosphatase
Poa1p
ADP-ribose 1''-phosphate phosphohydrolase
Systematic name:
ADP-D-ribose 1''-phosphate phosphohydrolase

Reaction

Comments:

The enzyme is highly specific for ADP-D-ribose 1''-phosphate. Involved together with EC 3.1.4.37, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1'',2''-cyclic phosphate (Appr>p), a by-product of tRNA splicing.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (45) [show] [UniProt]

References

  1. Shull, N. P., Spinelli, S. L., Phizicky, E. M.
    A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.
    Nucleic Acids Res. 33: 650-660 (2005). [PMID: 15684411]

[EC 3.1.3.84 created 2011]