EC - 3'(2'),5'-bisphosphate nucleotidase

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IntEnz Enzyme Nomenclature


Accepted name:
3'(2'),5'-bisphosphate nucleotidase
Other names:
3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase
3'-phosphoadenylylsulfate 3'-phosphatase
phosphoadenylate 3'-nucleotidase
Systematic name:
adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase



Also acts on 3'-phosphoadenylylsulfate, and on the corresponding 2'-phosphates.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008441
CAS Registry Number: 9025-83-6
UniProtKB/Swiss-Prot: (45) [show] [UniProt]


  1. Brungraber, E.G.
    Nucleotides involved in the enzymatic conjugation of phenols with sulfate.
    J. Biol. Chem. 233: 472-477 (1958).
  2. Farooqui, A.A. and Balasubramanian, A.S.
    Enzymatic dephosphorylation 3'-phosphoadenosine 5'-phosphosulfate to adenosine 5'-phosphosulfate in sheep brain.
    Biochim. Biophys. Acta 198: 56-65 (1970). [PMID: 4313079]
  3. Ramaswamy, S.G. and Jakoby, W.B.
    (2')3',5'-Bisphosphate nucleotidase.
    J. Biol. Chem. 262: 10044-10047 (1987). [PMID: 3038862]
  4. Tsang, M.L.-S. and Schiff, J.A.
    Properties of enzyme fraction A from Chlorella and copurification of 3' (2'), 5'-biphosphonucleoside 3' (2')-phosphohydrolase, adenosine 5'phosphosulfate sulfohydrolase and adenosine-5'-phosphosulfate cyclase activities.
    Eur. J. Biochem. 65: 113-121 (1976). [PMID: 179817]

[EC created 1961]