EC 3.1.3.53 - [myosin-light-chain] phosphatase

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IntEnz Enzyme Nomenclature
EC 3.1.3.53

Names

Accepted name:
[myosin-light-chain] phosphatase
Other names:
myosin light chain kinase phosphatase
myosin phosphatase
myosin-light-chain-phosphatase
protein phosphatase 2A
Systematic name:
[myosin-light-chain]-phosphate phosphohydrolase

Reactions

Comments:

The enzyme is composed of three subunits. The holoenzyme dephosphorylates myosin light chains and EC 2.7.11.31, [myosin-light-chain] kinase, but not myosin; the catalytic subunit acts on all three substrates.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050115
UniProtKB/Swiss-Prot:

References

  1. Pato, M.D. and Adelstein, R.S.
    Purification and characterization of a multisubunit phosphatase from turkey gizzard smooth muscle. The effect of calmodulin binding to myosin light chain kinase on dephosphorylation.
    J. Biol. Chem. 258: 7047-7054 (1983). [PMID: 6304072]

[EC 3.1.3.53 created 1986]