EC - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase

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IntEnz Enzyme Nomenclature


Accepted name:
[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase
Other names:
phosphopyruvate dehydrogenase phosphatase
pyruvate dehydrogenase phosphatase
[pyruvate dehydrogenase (lipoamide)]-phosphate phosphohydrolase
[pyruvate dehydrogenase (lipoamide)]-phosphatase
Systematic name:
[pyruvate dehydrogenase (acetyl-transferring)]-phosphate phosphohydrolase



A mitochondrial enzyme associated with EC pyruvate dehydrogenase (acetyl-transferring), in the pyruvate dehydrogenase complex.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00792
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004741
CAS Registry Number: 9073-70-5


  1. Linn, T.C., Pelley, J.W., Petit, F.H., Hucho, F., Randall, D.D. and Reed, L.J.
    α-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart.
    Arch. Biochem. Biophys. 148: 327-342 (1972). [PMID: 4401694]
  2. Reed, L.J., Damuni, Z. and Merryfield, M.L.
    Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation.
    Curr. Top. Cell. Regul. 27: 41-49 (1985). [PMID: 3004826]

[EC created 1978]