EC - Fructose-bisphosphatase

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IntEnz Enzyme Nomenclature


Accepted name:
Other names:
D-fructose 1,6-diphosphatase
D-fructose-1,6-bisphosphate phosphatase
fructose 1,6-bisphosphatase
fructose 1,6-bisphosphate 1-phosphatase
fructose 1,6-bisphosphate phosphatase
fructose 1,6-diphosphatase
fructose 1,6-diphosphate phosphatase
fructose bisphosphate phosphatase
fructose diphosphatase
fructose diphosphate phosphatase
hexose bisphosphatase
hexose diphosphatase
Systematic name:
D-fructose-1,6-bisphosphate 1-phosphohydrolase



The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00114
Structural data: CSA , EC2PDB
Gene Ontology: GO:0042132
CAS Registry Number: 9001-52-9
UniProtKB/Swiss-Prot: (540) [show] [UniProt]


  1. El-Badry, A.M.
    Hexosediphosphatase from spinach chloroplasts. Purification, crystallization and some properties.
    Biochim. Biophys. Acta 333 : 366-377 (1974).
  2. Gomori, G.
    J. Biol. Chem. 148 : 139-149 (1943).
  3. Mokrash, L.C. and McGilvery, R.N.
    Purification and properties of fructose-1,6-diphosphatase.
    J. Biol. Chem. 221 : 909-917 (1956).
  4. Pontremoli, S., Traniello, S., Luppis, B. and Wood, W.A.
    Fructose diphosphatase from rabbit liver. I. Purification and properties.
    J. Biol. Chem. 240 : 3459-3463 (1965). [PMID: 4284291]

[EC created 1961, modified 1976]