EC - FMN hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
FMN hydrolase
Other names:
FMN phosphatase
Systematic name:
FMN phosphohydrolase




Requires Mg2+. The enzyme, found in many isoforms purified from both bacteria and plants, is a member of the haloacid dehalogenase superfamily. Most of the isoforms have a wide substrate specificity [2], but isoforms specific for FMN also exist [3].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Sandoval, F. J., Roje, S.
    An FMN hydrolase is fused to a riboflavin kinase homolog in plants.
    J. Biol. Chem. 280 : 38337-38345 (2005). [PMID: 16183635]
  2. Kuznetsova, E., Proudfoot, M., Gonzalez, C. F., Brown, G., Omelchenko, M. V., Borozan, I., Carmel, L., Wolf, Y. I., Mori, H., Savchenko, A. V., Arrowsmith, C. H., Koonin, E. V., Edwards, A. M., Yakunin, A. F.
    Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.
    J. Biol. Chem. 281 : 36149-36161 (2006). [PMID: 16990279]
  3. Rawat, R., Sandoval, F. J., Wei, Z., Winkler, R., Roje, S.
    An FMN hydrolase of the haloacid dehalogenase superfamily is active in plant chloroplasts.
    J. Biol. Chem. 286 : 42091-42098 (2011). [PMID: 22002057]

[EC created 2016]