EC - Ribonuclease P

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IntEnz Enzyme Nomenclature


Accepted name:
ribonuclease P
Other name:
RNase P
Systematic name:



An RNA-containing enzyme, essential for tRNA processing; generates 5'-termini or mature tRNA molecules.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00558
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004526
CAS Registry Number: 71427-00-4 ((not distinguished from EC
UniProtKB/Swiss-Prot: (702) [show] [UniProt]


  1. Bikoff, E.K. and Gefter, M.L.
    In vitro synthesis of transfer RNA. I. Purification of required components.
    J. Biol. Chem. 250: 6240-6247 (1975). [PMID: 1099089]
  2. Bikoff, E.K., La Rue, B.F. and Gefter, M.L.
    In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities.
    J. Biol. Chem. 250: 6248-6255 (1975). [PMID: 1099090]
  3. Robertson, H.D., Altman, S. and Smith, J.D.
    Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor.
    J. Biol. Chem. 247: 5243-5251 (1972). [PMID: 4560501]

[EC created 1978, modified 1982]