EC - 2-aminobenzoylacetyl-CoA thioesterase

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IntEnz Enzyme Nomenclature


Accepted name:
2-aminobenzoylacetyl-CoA thioesterase
Other name:
pqsE (gene name)
Systematic name:
2-aminobenzoylacetyl-CoA hydrolase



The enzyme, characterized from the bacterium Pseudomonas aeruginosa, participates in the production of the signal molecule 2-heptyl-4(1H)-quinolone (HHQ).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Yu, S., Jensen, V., Seeliger, J., Feldmann, I., Weber, S., Schleicher, E., Haussler, S., Blankenfeldt, W.
    Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein.
    Biochemistry 48 : 10298-10307 (2009). [PMID: 19788310]
  2. Drees, S. L., Fetzner, S.
    PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules.
    Chem. Biol. 22 : 611-618 (2015). [PMID: 25960261]

[EC created 2016]