EC 3.1.2.32 - 2-aminobenzoylacetyl-CoA thioesterase

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IntEnz Enzyme Nomenclature
EC 3.1.2.32

Names

Accepted name:
2-aminobenzoylacetyl-CoA thioesterase
Other name:
pqsE (gene name)
Systematic name:
2-aminobenzoylacetyl-CoA hydrolase

Reaction

Comments:

The enzyme, characterized from the bacterium Pseudomonas aeruginosa, participates in the production of the signal molecule 2-heptyl-4(1H)-quinolone (HHQ).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Yu, S., Jensen, V., Seeliger, J., Feldmann, I., Weber, S., Schleicher, E., Haussler, S., Blankenfeldt, W.
    Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein.
    Biochemistry 48 : 10298-10307 (2009). [PMID: 19788310]
  2. Drees, S. L., Fetzner, S.
    PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules.
    Chem. Biol. 22 : 611-618 (2015). [PMID: 25960261]

[EC 3.1.2.32 created 2016]