EC - Phenylacetyl-CoA hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
phenylacetyl-CoA hydrolase
Systematic name:
phenylglyoxylyl-CoA hydrolase



This is the second step in the conversion of phenylacetyl-CoA to phenylglyoxylate, the first step being carried out by EC, phenylacetyl-CoA dehydrogenase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033880


  1. Rhee, S.K. and Fuchs, G.
    Phenylacetyl-CoA:acceptor oxidoreductase, a membrane-bound molybdenum-iron-sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica.
    Eur. J. Biochem. 262 : 507-515 (1999). [PMID: 10336636]
  2. Schneider, S. and Fuchs, G.
    Phenylacetyl-CoA:acceptor oxidoreductase, a new α-oxidizing enzyme that produces phenylglyoxylate. Assay, membrane localization, and differential production in Thauera aromatica.
    Arch. Microbiol. 169 : 509-516 (1998). [PMID: 9575237]

[EC created 2004]