EC - Dodecanoyl-[acyl-carrier-protein] hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
dodecanoyl-[acyl-carrier-protein] hydrolase
Other names:
dodecanoyl-acyl-carrier-protein hydrolase
dodecyl-acyl-carrier protein hydrolase
lauryl-acyl-carrier-protein hydrolase
lauryl-[acyl-carrier protein] hydrolase
dodecyl-[acyl-carrier protein] hydrolase
Systematic name:
dodecanoyl-[acyl-carrier-protein] hydrolase



Acts on the acyl-carrier-protein thioester of C12 and, with a much lower activity, C14 fatty acids. The derivative of oleic acid is hydrolysed very slowly (cf. EC, oleoyl-[acyl-carrier-protein] hydrolase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047381
CAS Registry Number: 137903-37-8


  1. Pollard, M.R., Anderson, L., Fan, C., Hawkins, D.J., Davies, H.M.
    A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica.
    Arch. Biochem. Biophys. 284 : 306-312 (1991). [PMID: 1989513]
  2. Davies, H.M., Anderson, L., Fan, C., Hawkins, D.J.
    Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica.
    Arch. Biochem. Biophys. 290 : 37-45 (1991). [PMID: 1898097]

[EC created 1999]