EC - S-formylglutathione hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
S-formylglutathione hydrolase
Systematic name:
S-formylglutathione hydrolase



Also hydrolyses S-acetylglutathione, but more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018738
CAS Registry Number: 50812-21-0
UniProtKB/Swiss-Prot: (36) [show] [UniProt]


  1. Uotila, L.
    Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases.
    Biochemistry 12 : 3938-3943 (1973). [PMID: 4200890]
  2. Uotila, L. and Koivusalo, M.
    Purification and properties of S-formylglutathione hydrolase from human liver.
    J. Biol. Chem. 249 : 7664-7672 (1974). [PMID: 4436331]
  3. Harms, N., Ras, J., Reijnders, W.N.M., van Spanning, R.J.M. and Stouthamer, A.H.
    S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?
    J. Bacteriol. 178 : 6296-6299 (1996). [PMID: 8892832]

[EC created 1978]