EC - Protein-glutamate methylesterase

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IntEnz Enzyme Nomenclature


Accepted name:
protein-glutamate methylesterase
Other names:
CheB methylesterase
chemotaxis-specific methylesterase
methyl-accepting chemotaxis protein methyl-esterase
methylesterase CheB
protein carboxyl methylesterase
protein methyl-esterase
protein methylesterase
protein-L-glutamate-5-O-methyl-ester acylhydrolase
Systematic name:
protein-L-glutamate-O5-methyl-ester acylhydrolase



Hydrolyses the products of EC (protein-L-isoaspartate(D-aspartate) O-methyltransferase), EC (isoorientin 3'-O-methyltransferase), EC (protein-glutamate O-methyltransferase) and EC (protein-S-isoprenylcysteine O-methyltransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC50122
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008984
CAS Registry Numbers: 69552-31-4 93792-01-9
UniProtKB/Swiss-Prot: (237) [show] [UniProt]


  1. Gagnon, C., Harbour, G. and Camato, R.
    Purification and characterization of protein methylesterase from rat kidney.
    J. Biol. Chem. 259: 10212-10215 (1984). [PMID: 6469959]
  2. Kehry, M.R., Doak, T.G. and Dahlquist, F.W.
    Stimulus-induced changes in methylesterase activity during chemotaxis in Escherichia coli.
    J. Biol. Chem. 259: 11828-11835 (1984). [PMID: 6384215]

[EC created 1989, modified 2002]