EC 3.1.1.32 - Phospholipase A1
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IntEnz Enzyme Nomenclature
EC 3.1.1.32
Names
Accepted name:
phospholipase A1
Systematic name:
phosphatidylcholine 1-acylhydrolase
Reaction
- phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate
Cofactor
Comments:
This enzyme has a much broader specificity than EC 3.1.1.4 phospholipase A2. Requires Ca2+.
Links to other databases
CAS Registry Number:
9043-29-2
References
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Purification and properties of phospholipase A-1 from rat and calf brain.Biochim. Biophys. Acta 159 : 304-316 (1968). [PMID: 5657461]
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A membrane-bound phospholipase A1 purified from Escherichia coli.Biochemistry 10 : 4447-4456 (1971). [PMID: 4946924]
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Intracellular phospholipases A.Biochim. Biophys. Acta 604 : 191-246 (1980). [PMID: 6252969]
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Isolation and properties of a phospholipase A1 activity from beef pancreas.Biochim. Biophys. Acta 348 : 197-209 (1974). [PMID: 4858811]
[EC 3.1.1.32 created 1972, modified 1976]