EC - Phospholipase A1

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IntEnz Enzyme Nomenclature


Accepted name:
phospholipase A1
Systematic name:
phosphatidylcholine 1-acylhydrolase




This enzyme has a much broader specificity than EC phospholipase A2. Requires Ca2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052740 , GO:0052739 , GO:0008970
CAS Registry Number: 9043-29-2
UniProtKB/Swiss-Prot: (45) [show] [UniProt]


  1. Gatt, S.
    Purification and properties of phospholipase A-1 from rat and calf brain.
    Biochim. Biophys. Acta 159: 304-316 (1968). [PMID: 5657461]
  2. Scandella, C.J. and Kornberg, A.
    A membrane-bound phospholipase A1 purified from Escherichia coli.
    Biochemistry 10: 4447-4456 (1971). [PMID: 4946924]
  3. van den Bosch, H.
    Intracellular phospholipases A.
    Biochim. Biophys. Acta 604: 191-246 (1980). [PMID: 6252969]
  4. van den Bosch, H., Aarsman, A.J. and van Deenen, L.L.M.
    Isolation and properties of a phospholipase A1 activity from beef pancreas.
    Biochim. Biophys. Acta 348: 197-209 (1974). [PMID: 4858811]

[EC created 1972, modified 1976]