EC 3.1.1.28 - Acylcarnitine hydrolase

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IntEnz Enzyme Nomenclature
EC 3.1.1.28

Names

Accepted name:
acylcarnitine hydrolase
Other names:
HACH
carnitine ester hydrolase
high activity acylcarnitine hydrolase
long-chain acyl-L-carnitine hydrolase
palmitoyl carnitine hydrolase
palmitoyl-L-carnitine hydrolase
palmitoylcarnitine hydrolase
Systematic name:
O-acylcarnitine acylhydrolase

Reaction

Comments:

Acts on higher fatty acid (C6 to C18) esters of L-carnitine; highest activity is with O-decanoyl-L-carnitine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047619
CAS Registry Number: 37278-42-5
UniProtKB/Swiss-Prot:

References

  1. Mahadevan, S. and Sauer, F.
    Carnitine ester hydrolase of rat liver.
    J. Biol. Chem. 244: 4448-4453 (1969). [PMID: 5806585]
  2. Mentlein, R., Reuter, G. and Heymann, E.
    Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function.
    Arch. Biochem. Biophys. 240: 801-810 (1985). [PMID: 4026306]

[EC 3.1.1.28 created 1972]