EC - Chlorophyllide a hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
chlorophyllide a hydrolase
Other name:
bciC (gene name)
Systematic name:
chlorophyllide-a hydrolase



This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green filamentous bacteria (Chloroflexaceae), catalyses the first committed step in the biosynthesis of bacteriochlorophylls c, d and e, the removal of the C-132-methylcarboxyl group from chlorophyllide a. The reaction is very similar to the conversion of pheophorbide a to pyropheophorbide a during chlorophyll a degradation, which is catalysed by EC, pheophorbidase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Liu, Z., Bryant, D. A.
    Identification of a gene essential for the first committed step in the biosynthesis of bacteriochlorophyll c.
    J. Biol. Chem. 286 : 22393-22402 (2011). [PMID: 21550979]

[EC created 2016]