EC - Trehalose 2-sulfotransferase

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IntEnz Enzyme Nomenclature


Accepted name:
trehalose 2-sulfotransferase
Other name:
Stf0 sulfotransferase
Systematic name:
3'-phosphoadenylyl-sulfate:α,α-trehalose 2-sulfotransferase



The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Mougous, J. D., Petzold, C. J., Senaratne, R. H., Lee, D. H., Akey, D. L., Lin, F. L., Munchel, S. E., Pratt, M. R., Riley, L. W., Leary, J. A., Berger, J. M., Bertozzi, C. R.
    Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.
    Nat. Struct. Mol. Biol. 11 : 721-729 (2004). [PMID: 15258569]
  2. Pi, N., Hoang, M. B., Gao, H., Mougous, J. D., Bertozzi, C. R., Leary, J. A.
    Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry.
    Anal. Biochem. 341 : 94-104 (2005). [PMID: 15866533]

[EC created 2014]