EC 2.8.2.2 - Alcohol sulfotransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.8.2.2

Names

Accepted name:
alcohol sulfotransferase
Other names:
3-hydroxysteroid sulfotransferase
3β-hydroxy steroid sulfotransferase
3β-hydroxysteroid sulfotransferase
5α-androstenol sulfotransferase
Δ5-3β-hydroxysteroid sulfokinase
HST
alcohol/hydroxysteroid sulfotransferase
cholesterol sulfotransferase
dehydroepiandrosterone sulfotransferase
estrogen sulfokinase
estrogen sulfotransferase
hydroxysteroid sulfotransferase
steroid alcohol sulfotransferase
steroid sulfokinase
steroid sulfotransferase
sterol sulfokinase
sterol sulfotransferase
Systematic name:
3'-phosphoadenylyl-sulfate:alcohol sulfotransferase

Reaction

Comments:

Primary and secondary alcohols, including aliphatic alcohols, ascorbic acid, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15 steroid sulfotransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004027
CAS Registry Number: 9032-76-2
UniProtKB/Swiss-Prot:

References

  1. Lyon, E.S. and Jakoby, W.B.
    The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases.
    Arch. Biochem. Biophys. 202: 474-481 (1980). [PMID: 6935986]
  2. Lyon, E.S., Marcus, C.J., Wang, J.-L. and Jakoby, W.B.
    Hydroxysteroid sulfotransferase.
    Methods Enzymol. 77: 206-213 (1981). [PMID: 6173569]

[EC 2.8.2.2 created 1961, modified 1980]