EC 2.8.1.3 - Thiosulfate—thiol sulfurtransferase
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IntEnz Enzyme Nomenclature
EC 2.8.1.3
Names
Accepted name:
thiosulfate—thiol sulfurtransferase
Other
names:
glutathione-dependent thiosulfate reductase
sulfane reductase
sulfane sulfurtransferase
sulfane reductase
sulfane sulfurtransferase
Systematic name:
thiosulfate:thiol sulfurtransferase
Reaction
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14505 [IUBMB]2glutathioneName origin: UniProt - CHECKED (C)Formula: C10H16N3O6S
Charge: -1ChEBI compound status: CHECKED (C)thiosulfateName origin: UniProt - CHECKED (C)Formula: HO3S2
Charge: -1ChEBI compound status: CHECKED (C)=glutathione disulfideName origin: UniProt - CHECKED (C)Formula: C20H30N6O12S2
Charge: -2ChEBI compound status: CHECKED (C)2H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)hydrogen sulfideName origin: UniProt - CHECKED (C)Formula: HS
Charge: -1ChEBI compound status: CHECKED (C)
Comments:
The primary product is glutathione hydrodisulfide, which reacts with glutathione to give glutathione disulfide and sulfide. L-Cysteine can also act as acceptor.
Links to other databases
Gene Ontology:
GO:0050337
CAS Registry Number:
111070-24-7
References
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The oxidation of thiosulfate and phosphorylation in extracts of Thiobacillus thioparus.J. Biol. Chem. 237 : 190-197 (1962).
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Separation of rhodanese and thiosulfate reductase activities in carp liver extracts.Acta Biol. Cracow Ser. Zoo. 15 : 97-103 (1972).
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Purification and steady-state kinetic analysis of yeast thiosulfate reductase.Arch. Biochem. Biophys. 195 : 211-222 (1979). [PMID: 383018]
[EC 2.8.1.3 created 1982]