EC 2.7.8.40 - UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase

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IntEnz Enzyme Nomenclature
EC 2.7.8.40

Names

Accepted name:
UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase
Other names:
WecP
UDP-GalNAc:polyprenol-P GalNAc-1-P transferase
UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Systematic name:
UDP-N-acetyl-α-D-galactosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-galactosaminephosphotransferase

Reaction

Comments:

The enzyme catalyses a step in the assembly of the repeating-unit of the O-antigen of the Gram-negative bacterium Aeromonas hydrophila AH-3. The enzyme shows no activity with UDP-N-acetyl-α-D-glucosamine (cf. EC 2.7.8.33, UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Merino, S., Jimenez, N., Molero, R., Bouamama, L., Regue, M., Tomas, J. M.
    A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.
    J. Bacteriol. 193 : 1943-1952 (2011). [PMID: 21335454]

[EC 2.7.8.40 created 2013]