EC 2.7.8.24 - Phosphatidylcholine synthase

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IntEnz Enzyme Nomenclature
EC 2.7.8.24

Names

Accepted name:
phosphatidylcholine synthase
Other names:
CDPdiglyceride-choline O-phosphatidyltransferase
PC synthase
CDP-diglyceride-choline O-phosphatidyltransferase
Systematic name:
CDP-diacylglycerol:choline O-phosphatidyltransferase

Reaction

Cofactor

Comments:

Requires divalent cations, with Mn2+ being more effective than Mg2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050520
CAS Registry Number: 243666-86-6
UniProtKB/Swiss-Prot: (10) [show] [UniProt]

References

  1. de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O.
    Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase.
    J. Biol. Chem. 274: 20011-20016 (1999). [PMID: 10391951]
  2. Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O.
    Cloning and characterization of the gene for phosphatidylcholine synthase.
    J. Biol. Chem. 275: 18919-18925 (2000). [PMID: 10858449]

[EC 2.7.8.24 created 2001]