EC 126.96.36.199 - Carboxyvinyl-carboxyphosphonate phosphorylmutase
IntEnz Enzyme Nomenclature
- 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2
Catalyses the transfer and decarboxylation of the carboxy(hydroxy)phosphoryl group, HOOC-P(O)(OH)- (phosphoryl being a 3-valent group), in the formation of an unusual C-P bond that is involved in the biosynthesis of the antibiotic bialaphos.
Links to other databases
Cloning, overexpression and mechanistic studies of carboxyphosphonoenolpyruvate mutase from Streptomyces hygroscopicus.Eur. J. Biochem. 209 : 735-743 (1992). [PMID: 1330557]
Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus.J. Bacteriol. 169 : 3482-3488 (1987). [PMID: 3611020]
[EC 188.8.131.52 created 1999]