EC 22.214.171.124 - GDP-D-glucose phosphorylase
IntEnz Enzyme Nomenclature
- GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP
The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-α-D-glucose. Activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose.
Links to other databases
A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals.J. Biol. Chem. 286 : 21511-21523 (2011). [PMID: 21507950]
[EC 126.96.36.199 created 2011]