EC - Molybdenum cofactor cytidylyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
molybdenum cofactor cytidylyltransferase
Other names:
CTP:molybdopterin cytidylyltransferase
MoCo cytidylyltransferase
Mo-MPT cytidyltransferase
Systematic name:
CTP:molybdenum cofactor cytidylyltransferase




Catalyses the cytidylation of the molybdenum cofactor. This modification occurs only in prokaryotes. Divalent cations such as Mg2+ or Mn2+ are required for activity. ATP or GTP cannot replace CTP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0061602


  1. Neumann, M., Mittelstadt, G., Seduk, F., Iobbi-Nivol, C., Leimkuhler, S.
    MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli.
    J. Biol. Chem. 284 : 21891-21898 (2009). [PMID: 19542235]
  2. Neumann, M., Seduk, F., Iobbi-Nivol, C., Leimkuhler, S.
    Molybdopterin dinucleotide biosynthesis in Escherichia coli: identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or cytosine nucleotides.
    J. Biol. Chem. 286 : 1400-1408 (2011). [PMID: 21081498]

[EC created 2011]