EC 2.7.7.76 - Molybdenum cofactor cytidylyltransferase

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IntEnz Enzyme Nomenclature
EC 2.7.7.76

Names

Accepted name:
molybdenum cofactor cytidylyltransferase
Other names:
MocA
CTP:molybdopterin cytidylyltransferase
MoCo cytidylyltransferase
Mo-MPT cytidyltransferase
Systematic name:
CTP:molybdenum cofactor cytidylyltransferase

Reaction

Cofactor

Comments:

Catalyses the cytidylation of the molybdenum cofactor. This modification occurs only in prokaryotes. Divalent cations such as Mg2+ or Mn2+ are required for activity. ATP or GTP cannot replace CTP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0061602
UniProtKB/Swiss-Prot:

References

  1. Neumann, M., Mittelstadt, G., Seduk, F., Iobbi-Nivol, C., Leimkuhler, S.
    MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli.
    J. Biol. Chem. 284: 21891-21898 (2009). [PMID: 19542235]
  2. Neumann, M., Seduk, F., Iobbi-Nivol, C., Leimkuhler, S.
    Molybdopterin dinucleotide biosynthesis in Escherichia coli: identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or cytosine nucleotides.
    J. Biol. Chem. 286: 1400-1408 (2011). [PMID: 21081498]

[EC 2.7.7.76 created 2011]