IntEnz - EC 2.7.7.58

EC 2 - Transferases

EC 2.7 - Transferring phosphorus-containing groups

EC 2.7.7 - Nucleotidyltransferases

EC 2.7.7.58 - (2,3-dihydroxybenzoyl)adenylate synthase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.7.7.58

Names

Accepted name:

(2,3-dihydroxybenzoyl)adenylate synthase

Other name:

2,3-dihydroxybenzoate-AMP ligase

Systematic name:

ATP:2,3-dihydroxybenzoate adenylyltransferase

Reaction

20229 [IUBMB]

2,3-dihydroxybenzoate

2,3-dihydroxybenzoate

Name origin: UniProt - CHECKED (C)

CHEBI:36654

Formula: C7H5O4
Charge: -1

ChEBI compound status: CHECKED (C)

+

ATP

ATP

Name origin: UniProt - CHECKED (C)

CHEBI:30616

Formula: C10H12N5O13P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

=

2,3-dihydroxybenzoyl-5'-AMP

2,3-dihydroxybenzoyl-5'-AMP

Name origin: UniProt - CHECKED (C)

CHEBI:57417

Formula: C17H17N5O10P
Charge: -1

ChEBI compound status: CHECKED (C)

+

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0008668

CAS Registry Number: 122332-73-4

UniProtKB/Swiss-Prot:

ENTE_ECO57

ENTE_ECOLI

References

Rusnak, F., Faraci, W.S. and Walsh, C.T.

Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product.

Biochemistry 28 : 6827-6835 (1989). [PMID: 2531000]

[EC 2.7.7.58 created 1992]