EC 2.7.7.10 - UTP—hexose-1-phosphate uridylyltransferase

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IntEnz Enzyme Nomenclature
EC 2.7.7.10

Names

Accepted name:
UTP—hexose-1-phosphate uridylyltransferase
Other names:
α-D-galactose 1-phosphate uridylyltransferase
UDPgalactose pyrophosphorylase
galactose 1-phosphate uridyltransferase
galactose 1-phosphate uridylyltransferase
galactose-1-phosphate uridylyltransferase
uridine diphosphate galactose pyrophosphorylase
uridine diphosphogalactose pyrophosphorylase
Gal-1-P uridylyltransferase
Systematic name:
UTP:α-D-hexose-1-phosphate uridylyltransferase

Reaction

Comments:

α-D-Glucose 1-phosphate can also act as acceptor, but more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0017103
CAS Registry Number: 9016-11-9

References

  1. Isselbacher, K.J.
    A mammalian uridinediphosphate galactose pyrophosphorylase.
    J. Biol. Chem. 232: 429-444 (1958).
  2. Kalckar, H.M.
    The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides.
    Biochim. Biophys. Acta 12: 250-264 (1953).
  3. Lee, L., Kimura, A. and Tochikura, T.
    Purification and properties of UDP-glucose (UDP-galactose) pyrophosphorylase from Bifidobacterium bifidum.
    J. Biochem. (Tokyo) 86: 923-928 (1979). [PMID: 500588]
  4. Lobelle-Rich, P.A. and Reeves, R.E.
    Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica.
    Mol. Biochem. Parasitol. 7: 173-182 (1983). [PMID: 6304512]

[EC 2.7.7.10 created 1961]