EC 2 - Transferases
EC 2.7 - Transferring phosphorus-containing groups
EC 2.7.7 - Nucleotidyltransferases
EC 2.7.7.1 - Nicotinamide-nucleotide adenylyltransferase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.7.7.1
Names
Accepted name:
nicotinamide-nucleotide adenylyltransferase
Other
names:
ATP:NMN adenylyltransferase
NAD+ pyrophosphorylase
NMN adenylyltransferase
adenosine triphosphate-nicotinamide mononucleotide transadenylase
diphosphopyridine nucleotide pyrophosphorylase
nicotinamide adenine dinucleotide pyrophosphorylase
nicotinamide mononucleotide adenylyltransferase
NMNAT
NAD+ pyrophosphorylase
NMN adenylyltransferase
adenosine triphosphate-nicotinamide mononucleotide transadenylase
diphosphopyridine nucleotide pyrophosphorylase
nicotinamide adenine dinucleotide pyrophosphorylase
nicotinamide mononucleotide adenylyltransferase
NMNAT
Systematic name:
ATP:nicotinamide-nucleotide adenylyltransferase
Reaction
- ATP + nicotinamide ribonucleotide = diphosphate + NAD+
Comments:
Nicotinate nucleotide can also act as acceptor. See also EC 2.7.7.18 nicotinate-nucleotide adenyltransferase.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Gene Ontology:
GO:0000309
CAS Registry Number:
9032-70-6
References
-
Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis.Biochem. J. 80 : 318-323 (1961).
-
The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast.Arch. Biochem. Biophys. 120 : 440-450 (1967). [PMID: 4291828]
-
Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate.J. Biol. Chem. 191 : 535-541 (1951).
[EC 2.7.7.1 created 1961]