IntEnz

EC 2.7.7.1 - Nicotinamide-nucleotide adenylyltransferase

IntEnz Enzyme Nomenclature
EC 2.7.7.1

Names

Reaction

• 21360 [IUBMB]
  ATP

  ATP

  Name origin: UniProt - CHECKED (C)

  CHEBI:30616

  Formula: C10H12N5O13P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

  +

  β-nicotinamide D-ribonucleotide

  beta-nicotinamide D-ribonucleotide

  Name origin: UniProt - CHECKED (C)

  CHEBI:14649

  Formula: C11H14N2O8P
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  =

  diphosphate

  diphosphate

  Name origin: UniProt - CHECKED (C)

  CHEBI:33019

  Formula: HO7P2
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  +

  NAD⁺

  NAD(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:57540

  Formula: C21H26N7O14P2
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

Comments:

Nicotinate nucleotide can also act as acceptor. See also EC 2.7.7.18 nicotinate-nucleotide adenyltransferase.

Links to other databases

References

1. Atkinson, M.R., Jackson, J.F. and Morton, R.K.
   Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis.
   Biochem. J. 80 : 318-323 (1961).
2. Dahmen, W., Webb, B. and Preiss, J.
   The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast.
   Arch. Biochem. Biophys. 120 : 440-450 (1967). [PMID: 4291828]
3. Kornberg, A. and Pricer, W.E.
   Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate.
   J. Biol. Chem. 191 : 535-541 (1951).

[EC 2.7.7.1 created 1961]