EC - Nicotinamide-nucleotide adenylyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
nicotinamide-nucleotide adenylyltransferase
Other names:
ATP:NMN adenylyltransferase
NAD+ pyrophosphorylase
NMN adenylyltransferase
adenosine triphosphate-nicotinamide mononucleotide transadenylase
diphosphopyridine nucleotide pyrophosphorylase
nicotinamide adenine dinucleotide pyrophosphorylase
nicotinamide mononucleotide adenylyltransferase
Systematic name:
ATP:nicotinamide-nucleotide adenylyltransferase



Nicotinate nucleotide can also act as acceptor. See also EC nicotinate-nucleotide adenyltransferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0000309
CAS Registry Number: 9032-70-6
UniProtKB/Swiss-Prot: (71) [show] [UniProt]


  1. Atkinson, M.R., Jackson, J.F. and Morton, R.K.
    Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis.
    Biochem. J. 80 : 318-323 (1961).
  2. Dahmen, W., Webb, B. and Preiss, J.
    The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast.
    Arch. Biochem. Biophys. 120 : 440-450 (1967). [PMID: 4291828]
  3. Kornberg, A. and Pricer, W.E.
    Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate.
    J. Biol. Chem. 191 : 535-541 (1951).

[EC created 1961]