EC 2 - Transferases
EC 2.7 - Transferring phosphorus-containing groups
EC 2.7.6 - Diphosphotransferases
EC 2.7.6.5 - GTP diphosphokinase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.7.6.5
Names
Accepted name:
GTP diphosphokinase
Other
names:
(p)ppGpp synthetase I
(p)ppGpp synthetase II
ATP-GTP 3'-diphosphotransferase
GPSI
GPSII
GTP pyrophosphokinase
guanosine 3',5'-polyphosphate synthase
guanosine 5',3'-polyphosphate synthetase
guanosine pentaphosphate synthetase
stringent factor
(p)ppGpp synthetase II
ATP-GTP 3'-diphosphotransferase
GPSI
GPSII
GTP pyrophosphokinase
guanosine 3',5'-polyphosphate synthase
guanosine 5',3'-polyphosphate synthetase
guanosine pentaphosphate synthetase
stringent factor
Systematic name:
ATP:GTP 3'-diphosphotransferase
Reaction
- ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate
Comments:
GDP can also act as acceptor.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0008728
CAS Registry Number:
63690-89-1
References
-
Stringent response of Bacillus stearothermophilus: evidence for the existence of two distinct guanosine 3',5'-polyphosphate synthetases.J. Bacteriol. 145 : 68-73 (1981). [PMID: 6161916]
-
Purification and properties of guanosine 5',3'-polyphosphate synthetase from Bacillus brevis.Biochemistry 15 : 4399-4403 (1976). [PMID: 184817]
[EC 2.7.6.5 created 1981]