IntEnz

EC 2.7.4.9 - DTMP kinase

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IntEnz Enzyme Nomenclature
EC 2.7.4.9

Names

Accepted name:

dTMP kinase

Other names:

TMPK
deoxythymidine 5'-monophosphate kinase
thymidine 5'-monophosphate kinase
thymidine monophosphate kinase
thymidylate kinase
thymidylate monophosphate kinase
thymidylic acid kinase
thymidylic kinase

Systematic name:

ATP:dTMP phosphotransferase

Reaction

13517 [IUBMB]

ATP

ATP

Name origin: UniProt - CHECKED (C)

CHEBI:30616

Formula: C10H12N5O13P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

dTMP

dTMP

Name origin: UniProt - CHECKED (C)

CHEBI:63528

Formula: C10H13N2O8P
Charge: -2

ChEBI compound status: CHECKED (C)

=

ADP

ADP

Name origin: UniProt - CHECKED (C)

CHEBI:456216

Formula: C10H12N5O10P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

dTDP

dTDP

Name origin: UniProt - CHECKED (C)

CHEBI:58369

Formula: C10H13N2O11P2
Charge: -3

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Protein domains and families: PROSITE:PDOC01034

Structural data: CSA , EC2PDB

Gene Ontology: GO:0004798

CAS Registry Number: 9014-43-1

UniProtKB/Swiss-Prot: (612) [show] [UniProt]

References

Hurwitz, J.

The enzymatic incorporation of ribonucleotides into polydeoxynucleotide material.

J. Biol. Chem. 234: 2351-2358 (1959).
Keilley, R.K.

Purification and properties of thymidine monophosphate kinase from mouse hepatoma.

J. Biol. Chem. 245: 4204-4212 (1970). [PMID: 4323166]
Nelson, D.J. and Carter, C.E.

Purification and characterization of thymidine 5-monophosphate kinase from Escherichia coli B.

J. Biol. Chem. 244: 5254-5262 (1969). [PMID: 4899016]

[EC 2.7.4.9 created 1965]

EC 2 - Transferases

EC 2.7 - Transferring phosphorus-containing groups

EC 2.7.4 - Phosphotransferases with a phosphate group as acceptor

EC 2.7.4.9 - DTMP kinase

Names

Reaction

Links to other databases

References