EC - Ribose 1,5-bisphosphate phosphokinase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
ribose 1,5-bisphosphate phosphokinase
Other names:
ribose 1,5-bisphosphokinase
ATP:ribose-1,5-bisphosphate phosphotransferase
Systematic name:
ATP:α-D-ribose-1,5-bisphosphate phosphotransferase



This enzyme, found in NAD supression mutants of Escherichia coli, synthesizes 5-phospho-α-D-ribose 1-diphosphate (PRPP) without the participation of EC, ribose-phosphate diphosphokinase. Ribose, ribose 1-phosphate and ribose 5-phosphate are not substrates, and GTP cannot act as a phosphate donor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033863
UniProtKB/Swiss-Prot: (40) [show] [UniProt]


  1. Hove-Jensen, B., Rosenkrantz, T.J., Haldimann, A. and Wanner, B. L.
    Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity (phosphoribosyl diphosphate forming): dual role in phosphonate degradation and NAD biosynthesis pathways.
    J. Bacteriol. 185 : 2793-2801 (2003). [PMID: 12700258]

[EC created 2006]