EC - Phosphomevalonate kinase

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IntEnz Enzyme Nomenclature


Accepted name:
phosphomevalonate kinase
Other names:
5-phosphomevalonate kinase
ATP:5-phosphomevalonate phosphotransferase
mevalonate phosphate kinase
mevalonate-5-phosphate kinase
mevalonic acid phosphate kinase
Systematic name:
ATP:(R)-5-phosphomevalonate phosphotransferase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00545
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004631
CAS Registry Number: 9026-46-4
UniProtKB/Swiss-Prot: (10) [show] [UniProt]


  1. Bloch, K., Chaykin, S., Phillips, A.H. and de Waard, A.
    Mevalonic acid pyrophosphate and isopentenyl pyrophosphate.
    J. Biol. Chem. 234: 2595-2604 (1959).
  2. Henning, U., Möslein, E.M. and Lynen, F.
    Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase.
    Arch. Biochem. Biophys. 83: 259-267 (1959).
  3. Levy, G.B. and Popják, G.
    Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase and phosphomevalonic kinase from liver.
    Biochem. J. 75: 417-428 (1960).

[EC created 1961]