EC - Protein arginine kinase

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IntEnz Enzyme Nomenclature


Accepted name:
protein arginine kinase
Other name:
Systematic name:
ATP:[protein]-L-arginine Nω-phosphotransferase



The enzyme, characterized from Gram-positive bacteria, is involved in the regulation of the bacterial stress response.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (67) [show] [UniProt]


  1. Fuhrmann, J., Schmidt, A., Spiess, S., Lehner, A., Turgay, K., Mechtler, K., Charpentier, E., Clausen, T.
    McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR.
    Science 324: 1323-1327 (2009). [PMID: 19498169]
  2. Elsholz, A. K., Turgay, K., Michalik, S., Hessling, B., Gronau, K., Oertel, D., Mader, U., Bernhardt, J., Becher, D., Hecker, M., Gerth, U.
    Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
    Proc. Natl. Acad. Sci. U.S.A. 109: 7451-7456 (2012). [PMID: 22517742]
  3. Schmidt, A., Trentini, D. B., Spiess, S., Fuhrmann, J., Ammerer, G., Mechtler, K., Clausen, T.
    Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.
    Mol. Cell Proteomics 13: 537-550 (2014). [PMID: 24263382]

[EC created 2014]