EC 2.7.11.28 - Tropomyosin kinase

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IntEnz Enzyme Nomenclature
EC 2.7.11.28

Names

Accepted name:
tropomyosin kinase
Other names:
tropomyosin kinase (phosphorylating)
STK
Systematic name:
ATP:tropomyosin O-phosphotransferase

Reaction

Comments:

The enzyme phosphorylates casein equally well, and histone and phosvitin to a lesser extent. The acceptor is a serine residue in the protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050359
CAS Registry Number: 90804-56-1

References

  1. deBelle, I. and Mak, A.S.
    Isolation and characterization of tropomyosin kinase from chicken embryo.
    Biochim. Biophys. Acta 925 : 17-26 (1987). [PMID: 3593768]
  2. Montgomery, K. and Mak, A.S.
    In vitro phosphorylation of tropomyosin by a kinase from chicken embryo.
    J. Biol. Chem. 259 : 5555-5560 (1984). [PMID: 6325440]
  3. Watson, M.H., Taneja, A.K., Hodges, R.S. and Mak, A.S.
    Phosphorylation of αα- and ββ-tropomyosin and synthetic peptide analogues.
    Biochemistry 27 : 4506-4512 (1988). [PMID: 3166994]

[EC 2.7.11.28 created 1990 as EC 2.7.1.132, transferred 2005 to EC 2.7.11.28]